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Table 1 Clinical characteristics of the cohort

From: Performance of a prognostic 31-gene expression profile in an independent cohort of 523 cutaneous melanoma patients

Clinical Characteristics n = 523
Median age (range), years 59 (18–92)
Median follow-up for patients without a metastatic event, years (range) 7.5 (5.0–16.5)
Recurrence/distant metastasis 142/111
Median time to first recurrence, years (range) 1.2 (0.0–10.0)
AJCC stage  
 I (total) 264 (50%)
 IA 108
 IB 76
 Unknown substagea 80
 II (total) 93 (18%)
 IIA 35
 IIB 26
 IIC 17
 Unknown substage 15
 III (total) 166 (32%)
 IIIA 69
 IIIB 57
 IIIC 35
 Unknown substage 5
Breslow thickness  
Median (range), mm 1.2 (0.1–29.0)
 ≤ 1 mm 223 (43%)
 >  1 mm 296 (56%)
 Unreported 4 (1%)
Mitotic index  
 <  1/mm2 99 (19%)
 ≥ 1/mm2 240 (46%)
 Unreported 184 (35%)
Ulceration  
 Absent 309 (59%)
 Present 133 (26%)
 Unreported 81 (15%)
SLN status  
 Untested 186 (36%)
 Negative 180 (34%)
 Positive 157 (30%)
GEP Class  
 Class 1 314 (60%)
 Class 2 209 (40%)
  1. SLN sentinel lymph node, GEP gene expression profile
  2. aSubstage information was not available in clinical documentation for these patients