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Table 1 Characteristics of patients and tumors (NA = not assessed, IDC = invasive ductal carcinoma, ILC = invasive lobular carcinoma)

From: Variations of circulating cardiac biomarkers during and after anthracycline-containing chemotherapy in breast cancer patients

Characteristics

Primary breast cancer patients (n = 45)

Median age (range) (y)

49 (26–78)

Estrogen receptor [n (%)]

29 (64)

Progesterone receptor [n (%)]

26 (58)

HER2 [n (%)]

17 (38)

Ki67 (median ± SD) (%)

30 ± 24

Initial T staging [n (%)]

 NA

0

 1

4 (9)

 2

23 (51)

 3

7 (16)

 4

11 (24)

Lymph node involvement [n (%)]

33 (73)

Tumor node metastasis (TNM) stage [n (%)]

 NA

0

 1

0

 2

26 (58)

 3

19 (42)

Scarff-Bloom-Richardson grading system [n (%)]

 NA

0

 1

0

 2

19 (42)

 3

26 (58)

Histologic subtype [n (%)]

 NA

0

 IDC

42 (93)

 ILC

3 (7)

 Others

0

Lymphovascular invasion [n (%)]

9 (20)

Cardiovascular risk factors [n (%)]

 Smoking

12 (27)

 Type 2 diabetes

4 (9)

 High blood pressure

9 (20)

 Obesity

7 (16)

 Dyslipidemia

21 (47)

 Chronic kidney disease

2 (4)

Left ventricular ejection fraction (median ± SD) (%)

 Before chemotherapy

64 ± 11

 After chemotherapy

60 ± 29