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Table 1 Patient characteristics

From: Analysis of tumour-infiltrating lymphocytes reveals two new biologically different subgroups of breast ductal carcinoma in situ

 

all pts. (n = 131)

DCIS pts. (n = 96)

miCa pts. (n = 35)

p value(*)

mean age [range]

56 [36–84]

56 [36–84]

54 [38–78]

NS

initial management

    

 lumpectomy

89 (68%)

68 (71%)

21 (60%)

NS

 mastectomy

42 (32%)

28 (29%)

14 (40%)

 

adjuvant treatment

    

 radiotherapy

89 (68%)

68 (71%)

21 (60%)

NS

 endocrine treatment

10 (8%)

1 (1.0%)

9 (26%)

<  0.0001

 cytotoxic treatment

2 (2%)

0 (0.0%)

2 (6%)

0.03

 observation

39 (30%)

27 (28%)

12 (34%)

NS

 trastuzumab

1 (1%)

0 (0%)

1 (3%)

NS

 recurrences

18 (14%)

14 (14%)

4 (11%)

NS

 DFS at 5 years

94% (n = 124)

94% (n = 91)

94% (n = 34)

NS

 DFS at 10 years

89% (n = 108)

88% (n = 78)

91% (n = 31)

  1. Abbreviations: DCIS pure DCIS, miCa microinvasive carcinoma, DFS disease-free survival, NS not significant, (*) characterizing the difference between DCIS and miCa