Fig. 6
From: Overexpression of endothelin B receptor in glioblastoma: a prognostic marker and therapeutic target?
In silico analysis of the protein structure and cellular localization of ETBR protein and its protein–protein interactions. A) The SWISS model of ETBR protein (transmembrane, G protein-coupled receptor), residues 111–398. Helices are shown in red, sheets in yellow, and loops in green. B) ETBR is primarily localized to the plasma membrane, cytosol, and nuclear membrane as revealed by COMPARTMENTS resource (http://compartments.jensenlab.org). C) Analysis of protein–protein interactions shows that ETBR primarily interact with eight proteins, which interact with 175 proteins. D) Gene ontology of ETBR neighborhood proteins