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Table 3 Common and rare sensitizing and not sensitizing mutations

From: Clinical management and outcome of patients with advanced NSCLC carrying EGFR mutations in Spain

Mutations (n = 168)a n (%)
Sensitizing mutations 157 (93.4)
 Common 134 (79.8)
  Exon 19 (all mutations) 96 (57.1)
  Exon 21 L858R 38 (22.6)
 Rare 23 (13.7)
  Exon 18 G719X 10 (5.6)
  Exon 18 G719A 3 (1.8)
  Exon 18 G719S 3 (1.8)
  Exon 21 L861Q 7 (4.2)
Not sensitizing mutations 7 (4.2)
 Exon 20 (all mutations) 7 (4.2)
Mutations of unknown significance 4 (2.4)
 Exon 21 L858Q 1 (0.6)
 Exon 21 E829Q 1 (0.6)
 Exon 21 R836C 1 (0.6)
 Exon 21 T854S 1 (0.6)
  1. aMutation type not available for 1 patient with exon 18 and 11 patients with exon 11 mutations