Skip to main content

Table 2 Methods, source and type of tumor samples for EGFR mutation testing

From: Clinical management and outcome of patients with advanced NSCLC carrying EGFR mutations in Spain

Methods for EGFR mutation testing (n = 181) n (%)
 Therascreen EGFR Mutation Test kit (ARMS) (Qiagen) 85 (47.0)
 RT-PCR (not specified) 26 (14.4)
 Fluorescent PCR fragment length analysis 22 (12.2)
 Direct sequencing 20 (11.0)
 Cobas EGFR Mutation Test kit (Roche) 9 (5.0)
 Allelic discrimination using fluorogenic probes 4 (2.2)
 Digital PCR 2 (1.1)
 Double PCR 1 (0.6)
 Non specified 16 (8.8)
Sample characteristics n (%)
 Biopsy (n = 121) 123 (68.7)
  Tumor tissue source
   Primary tumor 94 (77.7)
   Metastatic sites 27 (22.3)
 Cytology (n = 55) 55 (30.7)
  Tumor tissue source
   Primary tumor 35 (63.6)
   Metastatic sites 20 (36.4)
 Biopsy and cytology type (n = 174)
  Bronchoscopy 74 (42.5)
  FNA 56 (32.2)
  Thoracocentesis 16 (9.2)
  Surgery 14 (8.0)
  Biopsy (unspecified) 8 (4.6)
  Videothoracoscopy 5 (2.9)
  Tru-cut 4 (2.3)
  EBUS 1 (0.6)
  Data not available 2 (1.1)
  1. EBUS Endobronchial ultrasound, FNA Fine-needle aspiration