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Fig. 4 | BMC Cancer

Fig. 4

From: Monitoring the responsiveness of T and antigen presenting cell compartments in breast cancer patients is useful to predict clinical tumor response to neoadjuvant chemotherapy

Fig. 4

The predictive capacity of immune readouts for clinical response to chemotherapy. a Scatter plot of percentage of CD3 internalization vs. residual cancer burden (RCB) index in BC patients after chemotherapy (Pearson correlation = −0.583, p < 0.05). b Predictive value of TCR (CD3) internalization (left panel) and the delta percentage of CD83 expression in plasmacytoid DCs evaluated before therapy and compared in patients with or without better clinical response (pCR/RCB-I vs RCB-II respectively). c ROC curves of TCR internalization (AUC = 0.816, p = 0.0452), and delta percentage of CD83 expression in plasmacytoid DCs to predict tumor response (AUC = 0.825, p = 0.039). Box and whiskers 10–90%, Pearson correlation test, Mann-Whitney test, * p < 0.05, ** p < 0.01

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BMC Cancer

ISSN: 1471-2407

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