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Fig. 3 | BMC Cancer

Fig. 3

From: Optimising the chick chorioallantoic membrane xenograft model of neuroblastoma for drug delivery

Fig. 3

The effect of MLN8237 treatment on IMR-32 and BE(2)C cells. a Morphological changes of both cell lines after 3 days of 4 μM MLN8237 treatment. b shows the percentage change in proliferating cells in IMR-32 and BE(2)C following treatment with 4 μM MLN8237 for 3 days. c qPCR analysis of changes in target gene expression following 3 days of treatment. Each bar represents the mean of 3 technical replicates and 3 biological replicates. Although the trend in the changes of gene expression are the same as for ATRA the fold change is smaller and does not reach significance. Error bars (SE). Scale bar 100 μM

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