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Table 3 Adjusted hazard ratios (95% CI) for mortality in adults with ALL in England, 2001–12

From: Incidence, socioeconomic deprivation, volume-outcome and survival in adult patients with acute lymphoblastic leukaemia in England

Characteristic Adjusted hazard ratio (95% CI) for all 2921 patients
Age (y)
 - 18-29 1
 - 30-39 1.38 (1.15–1.66)
 - 40-49 1.69 (1.42–2.01)
 - 50-59 2.23 (1.89–2.62)
 - 60-69 3.72 (3.18–4.34)
 - 70-79 5.50 (4.68–6.46)
 - 80+ 9.02 (7.43–10.95)
Gender
 - Women 1
 - Men 1.04 (0.95–1.14)
Socioeconomic deprivation (by tertile)
 - Least deprived 1
 - Intermediate 1.21 (1.08–1.35)
 - Most deprived 1.16 (1.03–1.30)
Urban or rural areas
 - Urban 1
 - Rural 1.00 (0.89–1.13)
Time period
 - 2001-04 1
 - 2005-08 0.93 (0.84–1.03)
 - 2009-12 0.70 (0.62–0.79)
  Adjusted hazard ratio (95% CI) for subset of 465 patientsa
Record of chemotherapy
 - Yes 1
 - No 5.53 (3.98–7.69)
Hospital provider volume of ALL patients
 - >15 1
 - = <15 1.33 (1.03–1.73)
  1. aPatients diagnosed between 1st April 2008 and 31st March 2011 with all their admissions at a single hospital provider unit during this period. This analysis included chemotherapy and volume in addition to the other variables