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Table 3 Hazard ratios (HRs) of mortality, and corresponding 95% confidence intervals (CIs), according to pathological lymph nodes and lymph node ratio among 319 triple-negative breast cancers (TNBCs) with positive lymph nodes. Sardinia, Italy 1994–2015

From: Clinical and pathological factors influencing survival in a large cohort of triple-negative breast cancer patients

  

Number of deaths (%)

HRa (95% CI)

HRb (95% CI)

Pathological lymph nodes (pN)

 pN1

185

42 (22.7)

1.00c

1.00c

 pN2

88

21 (23.9)

1.37 (0.80–2.37)

1.13 (0.58–2.17)

 pN3

46

19 (41.3)

2.18 (1.23–3.84)

0.80 (0.34–1.87)

Lymph node ratio

  < 0.20

169

25 (14.8)

1.00c

1.00c

 0.21–0.65

93

29 (31.2)

2.47 (1.43–4.25)

2.44 (1.25–4.78)

  > 0.65

48

22 (45.8)

3.62 (1.96–6.68)

3.05 (1.35–6.87)

Missing

9

   
  1. aEstimates from multivariate proportional hazard regression models adjusted for study center and age at diagnosis. Estimates in bold are those significant at the 0.05 level. bEstimates further adjusted for TNM-T, TNM-N, TNM-M, necrosis, LVI, and Ki-67. cReference category