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Table 3 Hazard ratios (HRs) of mortality, and corresponding 95% confidence intervals (CIs), according to pathological lymph nodes and lymph node ratio among 319 triple-negative breast cancers (TNBCs) with positive lymph nodes. Sardinia, Italy 1994–2015

From: Clinical and pathological factors influencing survival in a large cohort of triple-negative breast cancer patients

   Number of deaths (%) HRa (95% CI) HRb (95% CI)
Pathological lymph nodes (pN)
 pN1 185 42 (22.7) 1.00c 1.00c
 pN2 88 21 (23.9) 1.37 (0.80–2.37) 1.13 (0.58–2.17)
 pN3 46 19 (41.3) 2.18 (1.23–3.84) 0.80 (0.34–1.87)
Lymph node ratio
  < 0.20 169 25 (14.8) 1.00c 1.00c
 0.21–0.65 93 29 (31.2) 2.47 (1.43–4.25) 2.44 (1.25–4.78)
  > 0.65 48 22 (45.8) 3.62 (1.96–6.68) 3.05 (1.35–6.87)
Missing 9    
  1. aEstimates from multivariate proportional hazard regression models adjusted for study center and age at diagnosis. Estimates in bold are those significant at the 0.05 level. bEstimates further adjusted for TNM-T, TNM-N, TNM-M, necrosis, LVI, and Ki-67. cReference category