| |
Number of deaths (%)
|
HRa (95% CI)
|
HRb (95% CI)
|
---|
Pathological lymph nodes (pN)
|
pN1
|
185
|
42 (22.7)
|
1.00c
|
1.00c
|
pN2
|
88
|
21 (23.9)
|
1.37 (0.80–2.37)
|
1.13 (0.58–2.17)
|
pN3
|
46
|
19 (41.3)
|
2.18 (1.23–3.84)
|
0.80 (0.34–1.87)
|
Lymph node ratio
|
< 0.20
|
169
|
25 (14.8)
|
1.00c
|
1.00c
|
0.21–0.65
|
93
|
29 (31.2)
|
2.47 (1.43–4.25)
|
2.44 (1.25–4.78)
|
> 0.65
|
48
|
22 (45.8)
|
3.62 (1.96–6.68)
|
3.05 (1.35–6.87)
|
Missing
|
9
| | | |
- aEstimates from multivariate proportional hazard regression models adjusted for study center and age at diagnosis. Estimates in bold are those significant at the 0.05 level. bEstimates further adjusted for TNM-T, TNM-N, TNM-M, necrosis, LVI, and Ki-67. cReference category