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Fig. 5 | BMC Cancer

Fig. 5

From: IMMUNEPOTENT CRP induces cell cycle arrest and caspase-independent regulated cell death in HeLa cells through reactive oxygen species production

Fig. 5

Nuclear alterations induced by I-CRP in HeLa cells. a Degradation of DNA in Cells treated with I-CRP (1.25 U/mL) for 16 h, 24 h, 48 h and 72 h or Etoposide for 48 h. b Nuclear size measured by Image-J software of cells treated with I-CRP for different times (16, 24, 48 h), and stained with Hoechst 33,342. The percentages refer to nuclear size represent as % control (non-treated nuclear size = 100%). c Nuclear morphology of cells treated with I-CRP for 16 h, 24 h and 48 h or etoposide (100 μM for 48 h), stained with Hoechst 33,342 and visualized by fluorescence microscopy (OLYMPUS IX70) (40X)

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