Fig. 4
From: Doxorubicin resistance in breast cancer cells is mediated by extracellular matrix proteins
Breast cancer cell line response to doxorubicin exposure when cultured in the absence of ECM proteins. Doxorubicin dose-response activity on MDA-MB-231 (a) and MCF-7 (b) cells cultured on PuraMatrix™ or Growth Factor Reduced (GRF) Matrigel™. Collective IC50 results of doxorubicin activity on MDA-MB-231 (c) and MCF-7 (d) cells cultured in the presence of PuraMatrix or GFR Matrigel. (e) Morphology of breast cancer cells cultured on PuraMatrix and exposed to doxorubicin (0.001-100 μM). # GraphPad Prism unable to calculate IC50 value, estimated from raw data. Significance values are: p ≤ 0.05 (*). Scale bar = 50 μm. Data are mean ± standard deviation