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Table 2 Single Marker Association in NMSC patients (n = 209) compared to different reference groups

From: Coordinated expression and genetic polymorphisms in Grainyhead-like genes in human non-melanoma skin cancers

GRHL3 Observed frequency (genotypes)a Expected frequency (genotypes)a Allelic OR (95%CI)
p-value
Genotypic OR (C/G vs C/C) (95%CI) p-value
SNP ID rs141193530 0.01667
(0/7/202)
ExAC database (Non-Finnish European) OR = 2.12 (1.0006 to 4.5021)
P = 0.0498
OR = 2.19 (1.0266 to 4.6798)
P = 0.0426
chromosomal localizationb chr1:24,669,459 exon 11 0.00796
(6/519/32827)
ref/alt C/G 1kGP database (European) OR = 3.41 (1.0760 to 10.8051)
P = 0.0371
OR = 3.45 (1.0828 to 11.0017)
P = 0.0362
consequence p.Pro455Ala 0.00497
(0/5/1001)
  1. agenotypes GG/CG/CC
  2. bposition according to GRCh37/hg19 genome build