Characteristic
|
OS
|
PFS
|
---|
P-value
|
HR (95% Cl)
|
P-value
|
HR (95% Cl)
|
---|
Age(>60y)
|
<0.001
|
2.493 (1.657–3.749)
|
0.250
|
1.228(0.865–1.745)
|
Ann Arbor stage(III,IV)
|
0.533
|
1.185(0.695–2.022)
|
0.295
|
1.254(0.821–1.914)
|
LDH(>245 U/L)
|
0.042
|
1.690(1.020–2.800)
|
0.018
|
1.642(1.087–2.479)
|
ECOG PS(≥2)
|
0.411
|
1.230(0.751–2.012)
|
0.022
|
1.579(1.069–2.330)
|
Extranodal sites(>1)
|
0.013
|
1.803(1.134–2.868)
|
0.187
|
1.305(0.879–1.937)
|
ICPS ≥ 2
|
0.001
|
2.476 (1.483–4.136)
|
0.019
|
1.611(1.080–2.404)
|
- Abbreviations: OS Overall survival, PFS Progression-free survival, HR Hazard Ratio, 95% Cl, 95% confidence limits, LDH Lactate dehydrogenase, ECOG PS Eastern Cooperative Oncology Group performance status, IPI International Prognostic Index, Hi High-intermediate, H High, ICPS Inflammation-based cumulative prognostic score