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Table 1 The relationship between miR-200a expression and clinicopathologic parameters in patients with breast cancer received preoperative chemotherapy

From: MicroRNA-200a confers chemoresistance by antagonizing TP53INP1 and YAP1 in human breast cancer

Clinicopathologic parameters

Number of cases

Median expression of miR-200a (normalized CT)a

P

Age,y

  

0.731

  ≤ 40

13

10.60 ± 2.870

 

  > 40

59

10.36 ± 2.939

 

Histological type

  

0.892

 DCIS

3

10.63 ± 1.572

 

 IDC

69

10.39 ± 2.959

 

Menstrual status

  

0.272

 Menstrual

38

10.05 ± 2.514

 

 Menopause

34

10.81 ± 3.285

 

TNM stage

  

0.918

 II

28

10.45 ± 3.601

 

 III

44

10.38 ± 2.412

 

Tumor size

  

0.839

 T1 + T2

32

10.48 ± 2.639

 

 T3 + T4

40

10.34 ± 3.138

 

Chemotherapy response

  

0.0021

 PD + SD

22

8.958 ± 2.586

 

 PR

50

11.04 ± 2.835

 

ER

  

0.277

 Negative

27

9.920 ± 2.648

 

 Positive

45

10.69 ± 3.045

 

PR

  

0.501

 Negative

23

10.06 ± 2.166

 

 Positive

49

10.56 ± 3.206

 

Her2

  

0.515

 Negative

52

10.54 ± 3.049

 

 Positive

20

10.04 ± 2.541

 

All cases

72

10.40 ± 2.908

 
  1. a normalized CT = CT miR-200a – CT U6