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Table 1 Demographic and clinico-pathological features of patients with and without liver metastases

From: Colorectal cancer liver metastases – a population-based study on incidence, management and survival

 

All patients (n = 1026)

No liver metastases (n = 754)

Liver metastases (n = 272)

Pa

Age (years)c

71.0 (62.2–79.9)

71.9 (63.5–81.0)

68.0 (60.1–77.4)

<0.001b

 Male

69.8 (62.1–77.5)

70.5 (62.3–78.1)

67.5 (60.3–75.1)

0.021b

 Female

72.6 (63.3–83.2)

74.2 (65.4–84.1)

68.9 (59.4–79.9)

0.001b

Age category

  < 50

55 (5.4)

35 (4.6)

20 (7.4)

0.001

 51–65

306 (29.8)

206 (27.3)

100 (36.8)

 66–80

413 (40.3)

309 (41.0)

104 (38.2)

  > 80

252 (24.5)

204 (27.1)

48 (17.6)

Sex ratio (M: F)

541: 485

384:370

157: 115

0.054

Primary tumour positiond

 Right-sided tumours

349 (34.9)

272 (36.9)

77 (29.4)

0.029

 Left-sided tumours

651 (65.1)

466 (63.1)

185 (70.6)

Primary tumour position

 Caecum/ascending colon

318 (31.0)

254 (33.7)

64 (23.5)

0.001

 Transverse colon

31 (3.0)

18 (2.4)

13 (4.8)

 Descending/sigmoid colon

277 (27.0)

187 (24.8)

90 (33.1)

 Rectum

374 (36.5)

279 (37.0)

95 (34.9)

 Unknown

11 (1.0)

10 (1.3)

1 (0.4)

 

 Multiple primary tumours

15 (1.5)

6 (0.8)

9 (3.3)

 

Tumour categorye

 T0

12 (1.2)

11 (1.5)

1 (0.4)

 

 T1

90 (8.8)

85 (11.3)

5 (1.8)

<0.001

 T2

145 (14.1)

138 (18.3)

7 (2.6)

 T3

520 (50.7)

389 (51.6)

131 (48.2)

 T4

201 (19.6)

105 (13.9)

96 (35.3)

 Unknown

58 (5.6)

26 (3.4)

32 (11.7)

 

Node categorye

 N0

513 (50.0)

470 (62.3)

43 (15.8)

<0.001

 N1

333 (32.5)

192 (25.5)

141 (51.8)

 N2

82 (8.0)

45 (6.0)

37 (13.6)

 Unknown

98 (9.5)

47 (6.2)

51 (18.8)

 

Metastatic categorye

 M0

773 (75.4)

689 (91.4)

84 (30.9)

<0.001

 M1

224 (21.8)

37 (4.9)

187 (68.8)

 Unknown

29 (2.8)

28 (3.7)

1 (0.3)

 

TNM-stagee

 Stage I

194 (18.9)

191 (25.3)

3 (1.1)

<0.001

 Stage II

299 (29.1)

274 (36.4)

25 (9.1)

 Stage III

267 (26.0)

213 (28.2)

54 (19.9)

 Stage IV

224 (21.8)

37 (4.9)

187 (68.8)

 Unknown

42 (0.4)

39 (5.2)

3 (1.1)

 
  1. Values in parentheses are percentages unless indicated otherwise
  2. aChi2 -test, except
  3. bWilcoxon rank-sum test
  4. cValues are median (i.q.r)
  5. dAccording to embryologic origin excluding unknown primaries (n = 11) and multiple primaries (n = 15)
  6. eStage at initial diagnosis