Skip to main content

Table 1 Demographic and clinico-pathological features of patients with and without liver metastases

From: Colorectal cancer liver metastases – a population-based study on incidence, management and survival

  All patients (n = 1026) No liver metastases (n = 754) Liver metastases (n = 272) Pa
Age (years)c 71.0 (62.2–79.9) 71.9 (63.5–81.0) 68.0 (60.1–77.4) <0.001b
 Male 69.8 (62.1–77.5) 70.5 (62.3–78.1) 67.5 (60.3–75.1) 0.021b
 Female 72.6 (63.3–83.2) 74.2 (65.4–84.1) 68.9 (59.4–79.9) 0.001b
Age category
  < 50 55 (5.4) 35 (4.6) 20 (7.4) 0.001
 51–65 306 (29.8) 206 (27.3) 100 (36.8)
 66–80 413 (40.3) 309 (41.0) 104 (38.2)
  > 80 252 (24.5) 204 (27.1) 48 (17.6)
Sex ratio (M: F) 541: 485 384:370 157: 115 0.054
Primary tumour positiond
 Right-sided tumours 349 (34.9) 272 (36.9) 77 (29.4) 0.029
 Left-sided tumours 651 (65.1) 466 (63.1) 185 (70.6)
Primary tumour position
 Caecum/ascending colon 318 (31.0) 254 (33.7) 64 (23.5) 0.001
 Transverse colon 31 (3.0) 18 (2.4) 13 (4.8)
 Descending/sigmoid colon 277 (27.0) 187 (24.8) 90 (33.1)
 Rectum 374 (36.5) 279 (37.0) 95 (34.9)
 Unknown 11 (1.0) 10 (1.3) 1 (0.4)  
 Multiple primary tumours 15 (1.5) 6 (0.8) 9 (3.3)  
Tumour categorye
 T0 12 (1.2) 11 (1.5) 1 (0.4)  
 T1 90 (8.8) 85 (11.3) 5 (1.8) <0.001
 T2 145 (14.1) 138 (18.3) 7 (2.6)
 T3 520 (50.7) 389 (51.6) 131 (48.2)
 T4 201 (19.6) 105 (13.9) 96 (35.3)
 Unknown 58 (5.6) 26 (3.4) 32 (11.7)  
Node categorye
 N0 513 (50.0) 470 (62.3) 43 (15.8) <0.001
 N1 333 (32.5) 192 (25.5) 141 (51.8)
 N2 82 (8.0) 45 (6.0) 37 (13.6)
 Unknown 98 (9.5) 47 (6.2) 51 (18.8)  
Metastatic categorye
 M0 773 (75.4) 689 (91.4) 84 (30.9) <0.001
 M1 224 (21.8) 37 (4.9) 187 (68.8)
 Unknown 29 (2.8) 28 (3.7) 1 (0.3)  
TNM-stagee
 Stage I 194 (18.9) 191 (25.3) 3 (1.1) <0.001
 Stage II 299 (29.1) 274 (36.4) 25 (9.1)
 Stage III 267 (26.0) 213 (28.2) 54 (19.9)
 Stage IV 224 (21.8) 37 (4.9) 187 (68.8)
 Unknown 42 (0.4) 39 (5.2) 3 (1.1)  
  1. Values in parentheses are percentages unless indicated otherwise
  2. aChi2 -test, except
  3. bWilcoxon rank-sum test
  4. cValues are median (i.q.r)
  5. dAccording to embryologic origin excluding unknown primaries (n = 11) and multiple primaries (n = 15)
  6. eStage at initial diagnosis