From: Colorectal cancer liver metastases – a population-based study on incidence, management and survival
All patients (n = 1026) | No liver metastases (n = 754) | Liver metastases (n = 272) | Pa | |
---|---|---|---|---|
Age (years)c | 71.0 (62.2–79.9) | 71.9 (63.5–81.0) | 68.0 (60.1–77.4) | <0.001b |
Male | 69.8 (62.1–77.5) | 70.5 (62.3–78.1) | 67.5 (60.3–75.1) | 0.021b |
Female | 72.6 (63.3–83.2) | 74.2 (65.4–84.1) | 68.9 (59.4–79.9) | 0.001b |
Age category | ||||
< 50 | 55 (5.4) | 35 (4.6) | 20 (7.4) | 0.001 |
51–65 | 306 (29.8) | 206 (27.3) | 100 (36.8) | |
66–80 | 413 (40.3) | 309 (41.0) | 104 (38.2) | |
> 80 | 252 (24.5) | 204 (27.1) | 48 (17.6) | |
Sex ratio (M: F) | 541: 485 | 384:370 | 157: 115 | 0.054 |
Primary tumour positiond | ||||
Right-sided tumours | 349 (34.9) | 272 (36.9) | 77 (29.4) | 0.029 |
Left-sided tumours | 651 (65.1) | 466 (63.1) | 185 (70.6) | |
Primary tumour position | ||||
Caecum/ascending colon | 318 (31.0) | 254 (33.7) | 64 (23.5) | 0.001 |
Transverse colon | 31 (3.0) | 18 (2.4) | 13 (4.8) | |
Descending/sigmoid colon | 277 (27.0) | 187 (24.8) | 90 (33.1) | |
Rectum | 374 (36.5) | 279 (37.0) | 95 (34.9) | |
Unknown | 11 (1.0) | 10 (1.3) | 1 (0.4) | |
Multiple primary tumours | 15 (1.5) | 6 (0.8) | 9 (3.3) | |
Tumour categorye | ||||
T0 | 12 (1.2) | 11 (1.5) | 1 (0.4) | |
T1 | 90 (8.8) | 85 (11.3) | 5 (1.8) | <0.001 |
T2 | 145 (14.1) | 138 (18.3) | 7 (2.6) | |
T3 | 520 (50.7) | 389 (51.6) | 131 (48.2) | |
T4 | 201 (19.6) | 105 (13.9) | 96 (35.3) | |
Unknown | 58 (5.6) | 26 (3.4) | 32 (11.7) | |
Node categorye | ||||
N0 | 513 (50.0) | 470 (62.3) | 43 (15.8) | <0.001 |
N1 | 333 (32.5) | 192 (25.5) | 141 (51.8) | |
N2 | 82 (8.0) | 45 (6.0) | 37 (13.6) | |
Unknown | 98 (9.5) | 47 (6.2) | 51 (18.8) | |
Metastatic categorye | ||||
M0 | 773 (75.4) | 689 (91.4) | 84 (30.9) | <0.001 |
M1 | 224 (21.8) | 37 (4.9) | 187 (68.8) | |
Unknown | 29 (2.8) | 28 (3.7) | 1 (0.3) | |
TNM-stagee | ||||
Stage I | 194 (18.9) | 191 (25.3) | 3 (1.1) | <0.001 |
Stage II | 299 (29.1) | 274 (36.4) | 25 (9.1) | |
Stage III | 267 (26.0) | 213 (28.2) | 54 (19.9) | |
Stage IV | 224 (21.8) | 37 (4.9) | 187 (68.8) | |
Unknown | 42 (0.4) | 39 (5.2) | 3 (1.1) |