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Table 3 Overall survival rates in 5 and 10 years of 84 patients with oral squamous cell carcinoma according to demographic features, risk factors, lymph node metastasis (pN), moesin and podoplanin, expression. A.C. Camargo Cancer Center, São Paulo, Brazil, 1963 to 2012

From: Moesin expression by tumor cells is an unfavorable prognostic biomarker for oral cancer

Variable Overall Survival p
5 years (%) 10 years (%)
Gender
 Male 33.8 15.4 0.145
 Female 8.3 8.3
Age
  ≤ 58 years 38.1 19.3 0.075
  > 58 years 22 9.8
Tobacco
 Yes 28.6 11.2 0.282
 No 25 25
Alcohol
 Yes 25 9.6 0.512
 No 31.6 12.6
Radioterapy
 Yes 32.4 11.8 0.802
 No 28.4 16.5
Muscle Infiltration
 Yes 30.9 11.5 0.313
 No 26.7 26.7
Pn
 pN0 39.5 21.2 0.081
 pN+ 21.7 8.1
Moesin
 Weak 38.5 23.8 0.024
 Strong 22.7 6.8
Podoplanin
 Weak 27.1 5.0 0.133
 Strong 34.3 25.7
  1. *pN+: Histopathological lymph node metastasis; pN0: Absence of lymph node metastasis, histopathologically
  2. p = value obtained by log-rank test
  3. p<0.05 was considered statistically significant