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Table 3 Overall survival rates in 5 and 10 years of 84 patients with oral squamous cell carcinoma according to demographic features, risk factors, lymph node metastasis (pN), moesin and podoplanin, expression. A.C. Camargo Cancer Center, São Paulo, Brazil, 1963 to 2012

From: Moesin expression by tumor cells is an unfavorable prognostic biomarker for oral cancer

Variable

Overall Survival

p

5 years (%)

10 years (%)

Gender

 Male

33.8

15.4

0.145

 Female

8.3

8.3

Age

  ≤ 58 years

38.1

19.3

0.075

  > 58 years

22

9.8

Tobacco

 Yes

28.6

11.2

0.282

 No

25

25

Alcohol

 Yes

25

9.6

0.512

 No

31.6

12.6

Radioterapy

 Yes

32.4

11.8

0.802

 No

28.4

16.5

Muscle Infiltration

 Yes

30.9

11.5

0.313

 No

26.7

26.7

Pn

 pN0

39.5

21.2

0.081

 pN+

21.7

8.1

Moesin

 Weak

38.5

23.8

0.024

 Strong

22.7

6.8

Podoplanin

 Weak

27.1

5.0

0.133

 Strong

34.3

25.7

  1. *pN+: Histopathological lymph node metastasis; pN0: Absence of lymph node metastasis, histopathologically
  2. p = value obtained by log-rank test
  3. p<0.05 was considered statistically significant