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Table 3 Univariate analyses for disease-specific survival

From: The prognostic value of TP53 mutations in hypopharyngeal squamous cell carcinoma

Variables

HR (95% CI)

P value

Tumor differentiation

W./M. vs. P.SCC

0.63 [0.13–3.09]

0.57

T classification

T1–3 vs. T4

1.12 [0.39–3.25]

0.83

Stage

Stage I/II vs. III/IV

2.30 [0.55–9.56]

0.25

Margin

Negative vs. Positive

2.08 [0.61–7.07]

0.24

No. of metastatic LNs

≤3 vs. ≥4

3.34 [1.04–10.7]

0.04

ENE

Absent vs. Present

3.34 [1.11–10.1]

0.03

PORT/CRT

Performed vs. Not performed

0.91 [0.33–2.53]

0.86

TP53 mutation

Wild-type vs. Mutation

3.32 [1.28–8.60]

0.01

p53 immunopositivity

Negative vs. Positive

0.87 [0.33–2.27]

0.77

  1. HR hazard ratio, 95% CI 95% confidence interval, W well differentiated, M moderately differentiated, P poorly differentiated, SCC squamous cell carcinoma, T tumor classification, No number, LN lymph node, ENE extranodal extension, PORT/CRT postoperative radiotherapy/chemoradiotherapy