From: The prognostic value of TP53 mutations in hypopharyngeal squamous cell carcinoma
Variables | HR (95% CI) | P value | |
---|---|---|---|
Tumor differentiation | W./M. vs. P.SCC | 0.63 [0.13–3.09] | 0.57 |
T classification | T1–3 vs. T4 | 1.12 [0.39–3.25] | 0.83 |
Stage | Stage I/II vs. III/IV | 2.30 [0.55–9.56] | 0.25 |
Margin | Negative vs. Positive | 2.08 [0.61–7.07] | 0.24 |
No. of metastatic LNs | ≤3 vs. ≥4 | 3.34 [1.04–10.7] | 0.04 |
ENE | Absent vs. Present | 3.34 [1.11–10.1] | 0.03 |
PORT/CRT | Performed vs. Not performed | 0.91 [0.33–2.53] | 0.86 |
TP53 mutation | Wild-type vs. Mutation | 3.32 [1.28–8.60] | 0.01 |
p53 immunopositivity | Negative vs. Positive | 0.87 [0.33–2.27] | 0.77 |