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Table 2 Correlation between RCC2 expression and clinicopathological features in ovarian cancer

From: RCC2 over-expression in tumor cells alters apoptosis and drug sensitivity by regulating Rac1 activation

Variables

Number

RCC2 expression

P value

Low expression

(−~+)

High expression

(++~+++)

Age

  ≤ 45

83

47

(56.6%)

36

(43.4%)

0.000a

  > 45

117

31

(26.5%)

86

(73.5%)

 

Type

 Normal

23

22

(95.7%)

1

(4.3%)

0.000b

 Malignant

141

49

(34.8%)

92

(65.2%)

 

 Metastasis

36

7

(19.4%)

29

(80.6%)

 

Tissue

 Ovarian

141

49

(34.8%)

92

(65.2%)

0.078a

 Othersc

36

7

(19.4%)

29

(80.6%)

 

Pathology

 Normal

23

22

(95.7%)

1

(4.3%)

0.000b

 Serous

69

8

(11.6%)

61

(88.4%)

 

 Mucinous

46

35

(76.1%)

11

(23.9%)

 

 Serous papillary

36

6

(16.7%)

30

(83.3%)

 

 Mucinous papillary

23

7

(30.4%)

16

(69.6%)

 

Grade

 1

59

33

(55.9%)

26

(44.1%)

0.000b

 2

58

11

(19.0%)

47

(81.0%)

 

 3

42

1

(2.4%)

41

(97.6%)

 

TNM stage

 T

  1

70

29

(41.4%)

41

(58.6%)

0.031a

  2–4

63

15

(23.8%)

48

(76.2%)

 

 N

  0

60

22

(36.7%)

38

(63.3%)

0.542a

  1

36

11

(30.6%)

25

(69.4%)

 

 M

  0

123

43

(35.0%)

80

(65.0%)

0.707b

  1

12

3

(25.0%)

9

(75.0%)

 
  1. “a” detected by Pearson’s χ2 tests, “b” detected by continuity corrected χ2 test. “c” others include three cases of lymph node, three cases of abdominal wall, nine cases of epiploon, three cases of groin, three cases of mesentery, nine cases of rectum, three cases of spleen, and three cases of vermiform appendix