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Table 2 Correlation between RCC2 expression and clinicopathological features in ovarian cancer

From: RCC2 over-expression in tumor cells alters apoptosis and drug sensitivity by regulating Rac1 activation

Variables Number RCC2 expression P value
Low expression
(−~+)
High expression
(++~+++)
Age
  ≤ 45 83 47 (56.6%) 36 (43.4%) 0.000a
  > 45 117 31 (26.5%) 86 (73.5%)  
Type
 Normal 23 22 (95.7%) 1 (4.3%) 0.000b
 Malignant 141 49 (34.8%) 92 (65.2%)  
 Metastasis 36 7 (19.4%) 29 (80.6%)  
Tissue
 Ovarian 141 49 (34.8%) 92 (65.2%) 0.078a
 Othersc 36 7 (19.4%) 29 (80.6%)  
Pathology
 Normal 23 22 (95.7%) 1 (4.3%) 0.000b
 Serous 69 8 (11.6%) 61 (88.4%)  
 Mucinous 46 35 (76.1%) 11 (23.9%)  
 Serous papillary 36 6 (16.7%) 30 (83.3%)  
 Mucinous papillary 23 7 (30.4%) 16 (69.6%)  
Grade
 1 59 33 (55.9%) 26 (44.1%) 0.000b
 2 58 11 (19.0%) 47 (81.0%)  
 3 42 1 (2.4%) 41 (97.6%)  
TNM stage
 T
  1 70 29 (41.4%) 41 (58.6%) 0.031a
  2–4 63 15 (23.8%) 48 (76.2%)  
 N
  0 60 22 (36.7%) 38 (63.3%) 0.542a
  1 36 11 (30.6%) 25 (69.4%)  
 M
  0 123 43 (35.0%) 80 (65.0%) 0.707b
  1 12 3 (25.0%) 9 (75.0%)  
  1. “a” detected by Pearson’s χ2 tests, “b” detected by continuity corrected χ2 test. “c” others include three cases of lymph node, three cases of abdominal wall, nine cases of epiploon, three cases of groin, three cases of mesentery, nine cases of rectum, three cases of spleen, and three cases of vermiform appendix