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Table 4 Overall survival and progression-free survival from the start of second-line targeted therapy according to MSKCC and IMDC risk groups (patients with evaluable MSKCC score, n = 1029; patients with evaluable IMDC score, n = 540)

From: Utilization and efficacy of second-line targeted therapy in metastatic renal cell carcinoma: data from a national registry

Prognostic score

n

Median OS (months) (95% CI)

Median PFS (months) (95% CI)

IMDC good

178

20.2 (13.6–26.8)

6.9 (5.0–8.8)

IMDC intermediate

314

17.0 (13.1–20.9)

5.8 (5.1–6.5)

IMDC poor

48

11.5 (5.3–17.7)

3.7 (2.8–4.6)

MSKCC good

378

19.2 (16.3–22.0)

7.3 (6.1–8.6)

MSKCC intermediate

596

15.7 (13.5–17.9)

6.0 (5.4–6.5)

MSKCC poor

55

5.5 (3.1–7.8)

3.7 (3.0–4.3)

  1. IMDC International Metastatic Renal Cell Carcinoma Database Consortium, MSKCC Memorial Sloan Kettering Cancer Center, OS overall survival, PFS progression-free survival