Table 3 Gender distribution of pediatric cancer in families with one - or more children with cancer
From: Predominance of girls with cancer in families with multiple childhood cancer cases
Diagnosis | FAM > 1 (n) | FAM1 (n) | LCCG-study (n) | General population [23] |
|---|---|---|---|---|
All diagnoses | 0.62 a,b (86) | 1.47 (487) | 1.36 (534) | 1.2 |
Leukemia | 0.30 a,b (30) | 1.30 (154) | 1.07 (170) | 1.2 |
CNS tumors | 0.47 a (22) | 1.63 (100) | 1.50 (110) | 1.2 |
Lymphoma | 2.67 (11) | 1.67 (72) | 1.79 (81) | 1.6 |
Histiocytosis | males only (2) | 1.75 (11) | 2.00 (12) | – |
Neuroblastoma | 0.33 (4) | 1.75 (22) | 1.40 (24) | 1.2 |
Retinoblastoma | 0.33 (3) | 1.00 (2) | 1.00 (4) | 1.1 |
Bone tumor | 0.50 (3) | 1.50 (40) | 1.50 (40) | 1.4 |
Hepatic tumor | 0.50 (3) | 2.00 (3) | 1.00 (6) | 1.4 |
Soft tissue sarcoma | males only (3) | 2.50 (28) | 2.75 (30) | 1.2 |
Germ-cell tumors | females only (1) | 0.83 (11) | 0.71 (12) | – |
Carcinomas | males only (1) | 1.50 (5) | 1.50 (5) | – |
Wilms tumor | 0.50 (3) | 1.27 (34) | 1.33 (35) | 0.9 |
Others | - (0) | 0.25 (5) | 0.25 (5) | – |