Acacia hydaspica ethyl acetate extract protects against cisplatin-induced DNA damage, oxidative stress and testicular injuries in adult male rats

Table 6 Effect of AHE treatment on testicular morphometric parameters in different experimental groups

Groups (n = 6)	Seminiferous tubule diameter (μm)	Seminiferous tubule epithelial height (μm)	Tubular lumen (μm)	Seminiferous tubule area (%)	Interstitial space (%)
Control	177.4 ± 2.04	70.90 ± 1.25	9.89 ± 0.63	86.29 ± 1.05	13.7 ± 1.05
CP	163.9 ± 1.60^***	21.15 ± 0.86^***	66.48 ± 0.61^***	45.44 ± 0.64^***	54.56 ± 0.64^***
AHE alone	173.7 ± 1.54⁺⁺⁺	71.52 ± 0.99⁺⁺⁺	9.99 ± 0.65⁺⁺⁺	86.69 ± 0.60⁺⁺⁺	13.31 ± 0.54⁺⁺⁺
CP + AHE	168.8 ± 1.24^**,++,##	24.18 ± 1.09^***,###	63.27 ± 0.72^***,+,###	69.33 ± 0.41^***,+++,###	30.67 ± 0.42^***,+++,###
AHE + CP	178.3 ± 1.62⁺⁺⁺	66.03 ± 0.68^*,+++	11.18 ± 0.60⁺⁺⁺	82.22 ± 0.60^**,+++	17.78 ± 0.60^**,+++
CP + Sily	173.8 ± 1.25⁺⁺⁺	66.33 ± 0.79^*,+++	11.43 ± 0.47⁺⁺⁺	82.44 ± 0.35699^**,+++	17.56 ± 0.35^**,++

n = 6/group; data presented as mean ± SEM;*** indicate significance from control group at p < 0.0001 probability level, +, +++ indicate significance from CP group at p < 0.05 and p < 0.0001 probability level, ^##, ^### indicate significance from AHE + CP group at p < 0.001 and p < 0.0001 probability level respectively

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