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Fig. 3 | BMC Cancer

Fig. 3

From: Acacia hydaspica ethyl acetate extract protects against cisplatin-induced DNA damage, oxidative stress and testicular injuries in adult male rats

Fig. 3

Microphotograph of rat testis (H&E stain) (a) CP group showing marked degenerative changes with severe germ cell aplasia, tubules with empty lumen, sloughing of the epithelial layer and degenerated interstitial space (b) CP + AHE group showing seminiferous tubule with elongating spermatids with a little degeneration in interstitial space and less sloughing in epithelial layer of cells (c) AHE + CP group showing filled lumen and compact seminiferous tubules with less interstitial space (d) Silymarin + CP group. AHE- A. hydaspica ethyl acetate extract, CP-Cisplatin, L-Lumen, SE-Seminiferous epithelium, ST-Seminiferous tubules, SB-Sperm bundles, Ld-Leydig cells, ST-Seminiferous tubules, SB-Sperm bundles, Ld-Leydig cells, VSE-vacuolated seminiferous epithelium, GCs- Germ cells, IT- Interstitial tissue, DST-distended seminiferous tubules, DIT-Disrupted interstitial tissue, DSE- disorganized seminiferous epithelium, EL-Empty lumen, DIC-Displaced interstitial cells, NGC-No germ cells

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