Fig. 2From: Inhibition of p38 MAPK activity leads to cell type-specific effects on the molecular circadian clock and time-dependent reduction of glioma cell invasivenessp38 MAPK activity is low in clock-disrupted Per1ldc/Per2ldc mutant fibroblasts. Representative western blots of protein extracts from WT and Per1ldc/Per2ldc fibroblasts (from Fig. 1) harvested at the indicated hour after serum shock probed with anti-phospho-p38 (pp38), anti-total p38 (p38) antibodies, and control anti-β-actin antibodies. A ½ and 1/10th fraction of WT protein harvested at 28 h was loaded as a reference. The data are plotted below (n = 3; ± SEM). The asterisk denotes a significant decrease in pp38 MAPK levels (p < 0.05)Back to article page