Fig. 1

Plexin-A1 is highly expressed in both tumor cells and vascular endothelial cells. a-b Representative images of immunohistochemical fluorescent staining show that plexin-A1 was not expressed in normal gastric tissues (a), but highly expressed in gastric cancer cells (b, arrow) and vascular endothelial cells within the gastric cancer (b, arrowheads). The lower 3 panels are the magnified regions of the upper panels. Scale bar, 25 μm. c-d Representative images of immunohistochemical staining with DAB show that plexin-A1 was not expressed in normal gastric tissues (c), but highly expressed in gastric cancer d, arrow) and vascular endothelial cells within the gastric cancer (d, arrowheads). The lower 3 panels are the magnified regions of the upper panels. Scale bar, 50 μm