N-glycosylation of serum proteins for the assessment of patients with IgD multiple myeloma

BMC Cancer

Table 3 Comparison between N-glycan markers and laboratory parameters in IgD MM patients

Correlations		NGA2F	NG1(6)A2F	NG1(3)A2F	NA2	NA3F2	NA4
Hb	r	0.242	0.531	0.642	0.233	−0.323	−0.241
(n = 20)	P	0.304	0.016^a	0.002^a	0.322	0.164	0.305
TP	r	−0.076	−0.085	−0.320	−0.604	−0.094	−0.520
(n = 20)	P	0.749	0.720	0.170	0.005^a	0.695	0.019+
ALB	r	−0.298	−0.096	−0.033	−0.041	−0.503	−0.418
(n = 20)	P	0.203	0.688	0.889	0.863	0.024^a	0.067
SLC ratio	r	−0.456	−0.531	−0.659	−0.353	−0.220	−0.176
(n = 15)	P	0.088	0.042^a	0.007^a	0.197	0.431	0.530
ULC ratio	r	−0.591	−0.549	−0.587	−0.411	−0.393	−0.166
(n = 16)	P	0.040^a	0.015+	0.017^a	0.114	0.132	0.583

Abbreviations: Hb haemoglobulin, TP total protein, ALB albumin, SLC serum light chain, ULC urine light chain
Using κ/λ ratio for IgD κ MM patients and λ/κ ratio for IgD λ MM patients
^arepresents N-glycan biomarkers with a significant correlation with corresponding laboratory indexes

ISSN: 1471-2407