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Table 1 Clinicopathologic characteristics of patients

From: Effect of total number of harvested lymph nodes on survival outcomes after curative resection for gastric adenocarcinoma: findings from an eastern high-volume gastric cancer center

Clinicopathologic variable

Mean (SD)/ Frequency (%) n = 4049

Age, in years

 Mean, SD

57.6 (11.9)

  < 65 years

2722 (67.2%)

  ≥ 65 years

1327 (32.8%)

Sex

 Male

2694 (66.5%)

 Female

1355 (33.5%)

BMI, in kg/m2

23.7 (3.1)

ASA

 I

1540 (38.0%)

 I

1991 (49.2%)

 III

187 (4.6%)

 Unknown

331 (8.2%)

pT size, in cm

4.6 (2.8)

pT category

 T1

2049 (50.6%)

 T2

595 (14.7%)

 T3

787 (19.4%)

 T4

618 (15.3%)

pN category

 N0

2465 (60.9%)

 N1

550 (13.6%)

 N2

440 (10.9%)

 N3

594 (14.7%)

Total number of pathologically positive lymph nodes

2.8 (6.3)

Total number of lymph nodes examined

 Mean, SD

42.9 (15.9)

 0–30

889 (22.0%)

 31–45

1597 (39.4%)

  > 45

1563 (38.6%)

pStage

 IA

1815 (44.8%)

 IB

501 (12.4%)

 IIA

423 (10.4%)

 IIB

330 (8.2%)

 IIIA

303 (7.5%)

 IIIB

341 (8.4%)

 IIIC

336 (8.3%)

Tumor location

 Proximal

683 (16.9%)

 Middle

1370 (33.8%)

 Distal

1916 (47.3%)

 Whole

80 (2.0%)

Histologic gradea

 Differentiated

1542 (38.1%)

 Undifferentiated

2456 (60.7%)

 Others

49 (1.2%)

 Unknown

2 (0.05%)

Borrmann type

 0

2214 (54.7%)

 I

51 (1.3%)

 II

374 (9.2%)

 III

1269 (31.3%)

 IV

121 (3.0%)

 V

19 (0.5%)

 Unknown

1 (0.02%)

Lauren type

 Intestinal

1899 (46.9%)

 Diffuse

1644 (40.6%)

 Mixed

359 (8.9%)

 Indeterminate/Unknown

147 (3.6%)

Lymphovascular invasion

 Present

1596 (39.4%)

 Absent

2340 (57.8%)

 Unknown

113 (2.8%)

Perineural invasion

 Present

948 (23.4%)

 Absent

2293 (56.6%)

 Unknown

808 (20.0%)

Resection type

 Subtotal

2892 (71.4%)

 Total

988 (24.4%)

 Extended

169 (4.2%)

Extent of lymph node dissection

 D1

126 (3.1%)

 D2

3867 (95.5%)

  > D2

46 (1.1%)

 Unknown

10 (0.2%)

Adjuvant chemotherapyb

 Yes

1002 (24.7%)

 No

3012 (74.4%)

 Unknown

35 (0.9%)

  1. Abbreviations: BMI body mass index, ASA American Society of Anesthesiology, pT pathologic tumor, pN pathologic nodal status
  2. aDifferentiated histology included papillary adenocarcinoma, well-differentiated tubular adenocarcinoma, and moderately differentiated adenocarcinoma. Undifferentiated histology included poorly differentiated adenocarcinoma, signet ring cell adenocarcinoma, and mucinous carcinoma. Others included adenosquamous, squamous, neuroendocrine, etc
  3. bAdjuvant chemotherapy was indicated in patients with Stage II disease and higher. Adjuvant chemotherapy after publication of S1 adjuvant therapy trial and initiation and subsequent publication of adjuvant capecitabine + oxaliplatin (XELOX) trial were either of the two. Prior to these trials, 5-fluorouracil-based chemotherapy was used