Skip to main content
Fig. 4 | BMC Cancer

Fig. 4

From: Melanoma cells replicate through chemotherapy by reducing levels of key homologous recombination protein RAD51 and increasing expression of translesion synthesis DNA polymerase ζ

Fig. 4

Reduced RAD51 mRNA levels in melanoma cells after cisplatin treatment. A375, C32, G361 melanoma cells, PEO4 ovarian cancer cells and MRC5v1 fibroblasts were treated with 3 μM cisplatin for 24, 48 or 72 h. RNA was extracted and RAD51 mRNA levels were determined by quantitative RT-PCR. RAD51 mRNA expression (±SEM, n = 3) is shown relative to β-actin and normalised to the level in untreated control (Cont.) cells

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us