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Table 2 Multivariable regression analysis of factors associated with treatment category

From: Trastuzumab without chemotherapy in the adjuvant treatment of breast cancer: subgroup results from a large observational study

Factora

Odds ratiob [P-value]

Multivariable model 1c

Multivariable model 2d

Age: <65 vs ≥65 years

1.51 [P = 0.0056]

1.57 [P = 0.0020]

ECOG performance: 0 vs 1–4

1.80 [P = 0.00003]

1.84 [P = 0.00001]

Grading: Grade 1/2 vs grade 3

0.77 [P = 0.062]

0.77 [P = 0.058]

Radiotherapy: no vs yes

0.53 [P = 0.00002]

–

  1. ECOG, Eastern Cooperative Oncology Group
  2. aFirst group mentioned is reference; − = not in model. bA value >1.0 indicates a higher probability of receiving Herceptin treatment without chemotherapy, as compared to reference group. cIncluding radiotherapy in the analysis. dExcluding radiotherapy from the analysis
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BMC Cancer

ISSN: 1471-2407

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