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Table 2 Multivariable regression analysis of factors associated with treatment category

From: Trastuzumab without chemotherapy in the adjuvant treatment of breast cancer: subgroup results from a large observational study

Factora Odds ratiob [P-value]
Multivariable model 1c Multivariable model 2d
Age: <65 vs ≥65 years 1.51 [P = 0.0056] 1.57 [P = 0.0020]
ECOG performance: 0 vs 1–4 1.80 [P = 0.00003] 1.84 [P = 0.00001]
Grading: Grade 1/2 vs grade 3 0.77 [P = 0.062] 0.77 [P = 0.058]
Radiotherapy: no vs yes 0.53 [P = 0.00002]
  1. ECOG, Eastern Cooperative Oncology Group
  2. aFirst group mentioned is reference; − = not in model. bA value >1.0 indicates a higher probability of receiving Herceptin treatment without chemotherapy, as compared to reference group. cIncluding radiotherapy in the analysis. dExcluding radiotherapy from the analysis