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Table 1 Grading criteria for each histologic change

From: Pathologic analysis of non-neoplastic parenchyma in renal cell carcinoma: a comprehensive observation in radical nephrectomy specimens

 

Grade 0

Grade 1

Grade 2

Grade 3

CI

no

<3 lymphoid aggregates

> = 3 lymphoid aggregates

diffuse inflammatory cell infiltrate

GS

no

<25% glomeruli sclerosed

25–50%

>50%

AS

no

both vessels wall thickening and luminal narrowing were slight

partial vessels luminal occlusion <= 50%

vessels luminal occlusion >50%

NS

no

thickened tubular basement membranes and hyaline sclerosis surrounding the tubules when examined at 20X

the grade1 changes along with interstitial fibrosis could be observed at 4X

diffuse tubular atrophy and drop-out with extensive hyaline sclerosis observed at 4X

  1. CI, chronic inflammation, was graded by using random objective 40X microscopic field; GS, glomerulosclerosis, was graded by using 10X objective field; AS, arteriosclerosis, was graded by using 40X field; NS, nephrosclerosis;