Fig. 3

Representative scheme of pharmacotherapy and laboratory tests. CT: computed tomography; CSF: cerebrospinal fluid; *On the day of cisplatin administration (total dose of 178 mg), the patient received vigorous hydration (3 L of saline solution 0.9%), diuretics (125 mL of mannitol 20%), electrolytes (20 mL of potassium chloride 19.1% and 10 mL of magnesium sulphate) and prophylaxis of acute emesis (20 mg of dexamethasone plus 24 mg of ondansetron); **Vancomycin 13th day dose: 1000 mg, after the 15th day: 500 mg; Cefepime 13th day dose: 2000 mg, after the 15th day: 1000 mg