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Table 4 Post-test probability of cancer for combinations of two abnormal blood tests

From: Routine blood tests and probability of cancer in patients referred with non-specific serious symptoms: a cohort study

  High LDH High alkaline phosphatase Thrombocytosis High WBC count High CRP Anaemia
Hypercalcaemia 62.8 (38.3; 82.1)
(n = 16)
46.6 (32.2; 61.7)
(n = 39)
46.8 (30.4; 63.9)
(n = 30)
47.1 (31.7; 63.2)
(n = 34)
42.6 (31.5; 54.5)
(n = 62)
34.1 (22.0; 48.6)
(n = 44)
Anaemia 26.2 (17.5; 37.2)
(n = 69)
29.9 (22.6; 38.3)
(n = 111)
23.9 (17.7; 31.4)
(n = 126)
28.5 (20.0; 39.0)
(n = 77)
28.9 (23.8; 34.6)
(n = 200)
 
High CRP 36.6 (26.4; 48.1)
(n = 67)
34.5 (28.0; 41.7)
(n = 145)
30.3 (23.8; 37.6)
(n = 138)
26.6 (20.7; 33.5)
(n = 149)
  
High WBC count 34.6 (20.6; 52.8)
(n = 29)
27.8 (19.3; 38.3)
(n = 76)
28.7 (20.4; 38.6)
(n = 84)
   
Thrombocytosis 37.8 (21.2; 57.7)
(n = 24)
26.4 (17.4; 37.9)
(n = 65)
    
High alkaline phosphatase 30.9 (21.3; 42.4)
(n = 66)
     
  1. The post-test probability of cancer is shown in each cell with the 95% CI shown in parenthesis. The number of patients with each combination is shown at the bottom of each cell. Pre-test probability of cancer: 12.2%
  2. Abbreviations: LDH lactate dehydrogenase, CRP: C-reactive protein, WBC count white blood cell count