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Table 2 Relationship between overexpression of Cullin7 and clinico-pathological parameters in HCC

From: Overexpression of Cullin7 is associated with hepatocellular carcinoma progression and pathogenesis

Parameter

n

Cullin7

negative(%)

positive(%)

P

Sex

ā€ƒMale

144

44(30.6)

100(69.4)

0.810

ā€ƒFemale

18

6(33.3)

12(66.7)

Ā 

Age(years)

ā€ƒ<50

97

32(33.0)

65(67.0)

0.474

ā€ƒā€‰ā‰„ā€‰50

65

18(27.7)

47(72.3)

Ā 

Tumor size(cm)

ā€ƒ<5

90

29(32.2)

61(67.8)

0.676

ā€ƒā€‰ā‰„ā€‰5

72

21(29.2)

51(70.8)

Ā 

Tumor numbers

ā€ƒSingle

116

34(29.3)

82(70.7)

0.497

ā€ƒmultitude

46

16(34.8)

30(65.2)

Ā 

AFP(Ī¼g/L)

ā€ƒ<400

98

31(31.6)

67(68.4)

0.793

ā€ƒā€‰ā‰„ā€‰400

64

19(29.7)

45(70.3)

Ā 

HBsAg

ā€ƒpositive

135

41(30.4)

94(69.6)

0.761

ā€ƒnegative

27

9(33.3)

18(66.7)

Ā 

Tumor thrombus

ā€ƒhave

69

11(15.9)

58(84.1)

0.000

ā€ƒno

93

39(41.9)

54(58.1)

Ā 

Lymph metastasis

ā€ƒhave

33

5(15.2)

28(84.8)

0.029

ā€ƒno

129

45(34.9)

84(65.1)

Ā 

Pathological grade

ā€ƒhigh

37

12(32.4)

25(67.6)

0.780

ā€ƒmoderately

112

33(29.5)

79(70.5)

Ā 

ā€ƒlow

13

5(38.5)

8(61.5)

Ā 

Hepatic function

ā€ƒChild A

106

34(32.1)

72(67.9)

0.820

ā€ƒChild B

36

11(30.6)

25(69.4)

Ā 

ā€ƒChild C

20

5(25.0)

15(75.0)

Ā 

Clinical stage

ā€ƒA

64

30(46.9)

34(53.1)

0.001

ā€ƒB

11

5(45.5)

6(54.5)

Ā 

ā€ƒC

67

12(17.9)

55(82.1)

Ā 

ā€ƒD

20

3(15.0)

17(85.0)

Ā