Table 3 Predictors of cancer diagnosis within one-yeara
Unadjusted analysis | Adjusted analysisb | ||||
|---|---|---|---|---|---|
OR (95%CI) | P-value | OR (95% CI) | P-value | ||
Age in years | 1.03 (1.01–1.04) | <0.001 | 1.03 (1.01–1.04) | 0.002 | |
Gender male | 0.86 (0.59–1.24) | 0.414 | – | – | |
Alcohol consumption above guidance | 1.27 (0.67–2.40) | 0.467 | – | – | |
Former/current smoker yes | 1.29 (0.86–1.92) | 0.223 | – | – | |
Symptoms | |||||
Weight loss | 0.89 (0.61–1.31) | 0.549 | – | – | |
Fatigue | 0.83 (0.56–1.23) | 0.348 | – | – | |
Loss of appetite | 1.11 (0.73–1.68) | 0.626 | – | – | |
Abdominal pain | 1.39 (0.88–2.18) | 0.158 | – | – | |
Indefinable pain | 1.18 (0.75–1.87) | 0.479 | – | – | |
Night sweats | 0.63 (0.37–1.08) | 0.092 | – | – | |
General illness | 0.86 (0.50–1.45) | 0.560 | – | – | |
Fever | 0.50 (0.21–1.18) | 0.114 | – | – | |
Other | 1.24 (0.72–2.16) | 0.440 | – | – | |
Abnormal biochemistry levels | |||||
Anemia | <7.3 for women <8.3 for men | 1.56 (1.05–2.31) | 0.028 | 1.63 (1.02–2.60) | 0.040 |
Leucocytopenia | <3.5 × 109 | 3.45 (1.15–10.39) | 0.028 | 2.01 (0.52–7.74) | 0.311 |
Leucocytosis | >8.8 × 109 | 2.38 (1.62–3.50) | <0.001 | 2.06 (1.34–3.15) | <0.001 |
Thrombocytopenia | <145 × 109 | 3.47 (1.77–6.81) | <0.001 | 4.13 (2.02–8.47) | <0.001 |
Thrombocytosis | >390 × 109 | 1.89 (1.16–3.07) | 0.010 | 1.67 (0.96–2.91) | 0.071 |
Elevated ESRc | >15 | 1.82 (1.05–3.15) | 0.033 | 1.29 (0.70–2.37) | 0.411 |
Elevated LDHd | > 205 U/l | 1.90 (1.30–2.79) | 0.001 | 1.64 (1.07–2.52) | 0.023 |
Elevated CRPe | >10 mg/l | 2.70 (1.84–3.97) | <0.001 | 2.56 (1.66–3.95) | <0.001 |