Table 3 Sensitivity and specificity estimates (MSI-L categorised as an index test negative result)
Author, year | Sensitivity (%) | Specificity (%) |
|---|---|---|
Single-gate, population-based samples | ||
 Poynter, 2008a [21] | 100.0 (93.9, 100.0) | 61.1 (57.0, 65.1) |
 Barnetson, 2006 [16] | 66.7 (47.2, 82.7) | 92.5 (89.1, 95.2) |
 Southey, 2005 [23] | 72.2 (46.5, 90.3) | 87.8 (73.8, 95.9) |
Single-gate, high-risk samples | ||
 Caldes, 2004b [17] | 79.4 (62.1, 91.3) | – |
 Mueller, 2009 [19] | 91.3 (72.0, 98.9) | – |
 Overbeek, 2007b [20] | 90.0 (59.6, 98.2) | – |
 Poynter, 2008c [21] | 86.8 (71.9, 95.6) | – |
 Shia, 2005b [22] | 100.0 (85.8, 100.0) | – |
Reference standard positive study | ||
 Hendriks, 2003 [18] | 88.0 (68.8, 97.5) | – |