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Fig. 3 | BMC Cancer

Fig. 3

From: Intra-tumor heterogeneity in breast cancer has limited impact on transcriptomic-based molecular profiling

Fig. 3

Intra tumor transcriptomic variation of ER, PR, HER2 and MKI67. mRNA expression levels of (a) ER (b) PR (c) HER2 and (d) MKI67 across tumor pieces from 12 patients. e Heterogeneity assessment of whole tumor section after immunohistochemical staining of the biomarkers ER, PR HER2, Ki-67 and tumor growth patterns (morphology). Assessments were performed by a board certified pathologist at Karolinska University Laboratory (LW). Green blocks represents homogeneous expression, while light brown colour indicates heterogeneous expression pattern across the whole tumor

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