Table 3 Logistic regression analysis verifying the risk factors for early termination of chemotherapy (N = 31)
Odds ratio | 95% confidence interval | p-value | |
|---|---|---|---|
Univariate analysis | |||
Age | 0.93 | 0.722–1.20 | 0.575 |
ECOG Performance status = 2 | 0.449 | 0.100–2.01 | 0.295 |
Brinkman Index | 1.00 | 0.999–1.00 | 0.655 |
Emphysema | 0.794 | 0.112–5.66 | 0.818 |
Diabetes melitus | 2.23 | 0.497–10.0 | 0.295 |
Squamous cell carcinoma | 0.889 | 0.135–5.85 | 0.902 |
Major diameter of the primary site | 1.01 | 0.973–1.04 | 0.672 |
Brain metastasis | 2.12 | 0.349–13.0 | 0.414 |
Bone metastasis | 9.92 | 1.75–56.3 | 0.00961 |
Liver metastasis | 0.900 | 0.0723–11.2 | 0.935 |
Adrenal gland metastasis | 7.12 | 0.640–79.3 | 0.110 |
Carboplatin-based doublet therapy | 1.06 | 0.229–4.92 | 0.939 |
Lymphocyte count | 1 | 0.999–1.00 | 0.866 |
Hemoglobin | 0.637 | 0.392–1.04 | 0.0691 |
Albumin | 0.117 | 0.0168–0.811 | 0.0299 |
Lactate dehydrogenase | 1.01 | 0.999–1.02 | 0.0979 |
Calcium | 1.19 | 0.632–2.24 | 0.59 |
C-reactive protein | 1.15 | 0.897–1.48 | 0.267 |
Multivariate analysis | |||
Bone metastasis | 10.9 | 1.52–77.9 | 0.0174 |
Albumin | 0.0886 | 0.00791–0.992 | 0.0493 |