Table 2 Survival analysis of OS
From: Clinical significance of PCDH10 promoter methylation in diffuse large B-cell lymphoma
OS | ||||
|---|---|---|---|---|
HR_U(95%CI) | p value | HR_M(95%CI) | p value | |
Age at diagnosis | ||||
<60y | 1.000 | |||
≥ 60y | 1.393(0.549–3.535) | 0.485 | ||
Sex | ||||
Male | 1.000 | |||
Female | 0.426(0.160–1.137) | 0.088 | ||
Primary site | ||||
Extranodal | 1.000. | |||
Nodala | 2.267(0.744-6.911) | 0.150 | ||
IPI risk category | ||||
Low | 1.000 | 1.000 | ||
Low-intermediate | 2.029(0.545–7.559) | 0.292 | 2.510(0.669–9.421) | 0.173 |
High-intermediate | 3.385(0.976–11.746) | 0.055 | 2.836(0.815–9.873) | 0.101 |
High | 5.487(1.467–20.517) | 0.011 | 6.986(1.845–26.450) | 0.004 |
Treatment | ||||
RCHOP | 1.000 | |||
Resection & RCHOP | 0.152(0.020–1.145) | 0.067 | ||
Hans Algorithm | ||||
GCB | 1.000 | |||
Non-GCB | 1.419(0.505–3.984) | 0.506 | ||
PCDH10 Methylation | ||||
No | 1.000 | 1.000 | ||
Yes | 3.547(1.166–10.791) | 0.026 | 4.045(1.287–12.711) | 0.017 |
MYC FISH Breakapart | ||||
No | 1.000 | |||
Yes | 1.285(0.170–9.713) | 0.808 | ||