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Table 4 Spearman Correlation Analysis (n = 236)

From: Insulin-like growth factor receptor and sphingosine kinase are prognostic and therapeutic targets in breast cancer

Variables

Spearman Coefficient

p-value

IGF1R

 p-IGF1R

0.076

0.245

 SphK1

0.139

0.033*

IGF1R (ER + ve)

 p-IGF1R

0.001

0.993

 SphK1

0.261

0.001*

IGF1R (ER-ve)

 cp-IGF1R

0.126

0.295

 SphK1

0.01

0.936

P-IGF1R

 SphK1

0.054

0.412

Age ≥ 51y

 p-IGF1R

0.036

0.580

 IGF1R

−0.147

0.025*

 SphK1

0.103

0.115

Grade

 p-IGF1R

−0.189

0.004*

 IGF1R

−0.35

0.591

 SphK1

0.083

0.202

ER Status

 p-IGF1R

0.177

0.007*

 IGF1R

0.240

0.000*

 SphK1

−0.227

0.000*

PR Status

 p-IGF1R

0.117

0.078

 IGF1R

0.269

0.000*

 SphK1

−0.192

0.003*

HER2 Status

 p-IGF1R

−0.206

0.002*

 IGF1R

0.046

0.487

 SphK1

−0.110

0.095

  1. *p-value significant; ≤0.05