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Table 3 Hazard ratios (HRs) a and 95% confidence intervals (CIs) for the association between metabolic dysregulation factors and cancer mortality

From: Metabolic dysregulation and cancer mortality in a national cohort of blacks and whites

  Black (N = 287) b White (N = 497) b All (N = 784) b p valueinteraction c
Obesity
 1st Quartile (Ref) Referent Referent Referent 0.25
 2nd Quartile 0.69 (0.48–0.98) 0.77 (0.60–0.99) 0.77 (0.62–0.94)  
 3rd Quartile 0.57 (0.37–0.88) 0.68 (0.50–0.94) 0.72 (0.56–0.93)  
 4th Quartile 0.63 (0.38–1.06) 0.71 (0.47–1.07) 0.84 (0.61–1.16)  
Cholesterol
 1st Quartile (Ref) Referent Referent Referent 0.27
 2nd Quartile 0.92 (0.66–1.28) 0.68 (0.52–0.88) 0.77 (0.63–0.94)  
 3rd Quartile 0.76 (0.53–1.09) 0.83 (0.64–1.08) 0.81 (0.65–0.99)  
 4th Quartile 0.87 (0.61–1.25) 0.86 (0.66–1.13) 0.86 (0.70–1.07)  
Blood Pressure
 1st Quartile (Ref) Referent Referent Referent 0.55
 2nd Quartile 1.02 (0.68–1.54) 1.06 (0.81–1.39) 1.06 (0.85–1.32)  
 3rd Quartile 0.89 (0.57–1.39) 0.87 (0.63–1.21) 0.89 (0.69–1.16)  
 4th Quartile 0.78 (0.48–1.25) 0.92 (0.64–1.31) 0.86 (0.65–1.14)  
Lipids
 1st Quartile (Ref) Referent Referent Referent 0.55
 2nd Quartile 1.28 (0.91–1.79) 0.95 (0.70–1.29) 1.07 (0.85–1.33)  
 3rd Quartile 1.12 (0.73–1.74) 0.92 (0.64–1.33) 1.00 (0.76–1.32)  
 4th Quartile 1.42 (0.86–2.32) 1.20 (0.81–1.79) 1.30 (0.96–1.77)  
Height
 1st Quartile (Ref) Referent Referent Referent 0.07
 2nd Quartile 0.90 (0.60–1.33) 1.00 (0.74–1.36) 0.97 (0.77–1.23)  
 3rd Quartile 1.34 (0.89–2.03) 0.86 (0.61–1.23) 1.04 (0.80–1.36)  
 4th Quartile 0.91 (0.56–1.49) 0.83 (0.56–1.22) 0.88 (0.65–1.19)  
Glucose
 1st Quartile (Ref) Referent Referent Referent 0.58
 2nd Quartile 1.28 (0.88–1.85) 1.20 (0.91–1.58) 1.23 (0.99–1.54)  
 3rd Quartile 1.15 (0.78–1.68) 1.23 (0.93–1.62) 1.21 (0.97–1.51)  
 4th Quartile 1.57 (1.10–2.23) 1.21 (0.90–1.62) 1.35 (1.08–1.69)  
# Factor Variables in 4th Quartile
 0 (Referent) Referent Referent Referent 0.08
 1 0.83 (0.56–1.21) 1.60 (1.16–2.19) 1.27 (0.99–1.62)  
 2 0.92 (0.62–1.36) 1.52 (1.08–2.14) 1.25 (0.97–1.62)  
 3+ 1.02 (0.65–1.62) 1.39 (0.94–2.07) 1.23 (0.91–1.66)  
  1. aAnalysis based on 19,963 REGARDS participants with non-missing data on all factor analysis component variables. Models adjusted for age, sex, race (all model only), education, region, income, tobacco use, alcohol use, and baseline chronic medical conditions, and hs-CRP
  2. b N = number of cancer death events
  3. c Interaction significance between race*factor using Wald test. Bold indicates statistically significant at 0.05 alpha level