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Table 2 Hazard ratios (HRs)a and 95% confidence intervals for the association between metabolic syndrome (MetS) and cancer mortality

From: Metabolic dysregulation and cancer mortality in a national cohort of blacks and whites

 

HR (95% CI)

Black

(N = 402)b

White

(N = 595)b

All

(N = 997)b

p valueinteraction c

Metabolic Syndrome

1.32 (1.01–1.72)

1.18 (0.94–1.48)

1.22 (1.03–1.45)

0.28

Components

 High WC

1.36 (0.75–2.46)

1.32 (0.73–2.36)

1.30 (0.86–1.96)

0.07

 Elevated Triglycerides

0.96 (0.71–1.28)

1.04 (0.86–1.25)

1.00 (0.86–1.16)

0.91

 Reduced HDL Cholesterol

1.30 (1.02–1.64)

1.27 (1.03–1.55)

1.27 (1.09–1.48)

0.27

 Elevated blood pressure

1.43 (0.96–2.15)

0.97 (0.73–1.28)

1.11 (0.89–1.40)

0.89

 Elevated fasting glucose

1.40 (1.09–1.81)

1.02 (0.83–1.26)

1.16 (0.99–1.36)

0.57

# Metabolic Syndrome Components

 0 (Referent)

Referent

Referent

Referent

0.98

 1

1.28 (0.73–2.24)

1.09 (0.78–1.52)

1.15 (0.86–1.53)

 

 2

1.63 (0.92–2.88)

1.07 (0.74–1.54)

1.24 (0.91–1.68)

 

 3

1.89 (1.02–3.49)

1.23 (0.82–1.85)

1.41 (1.01–1.97)

 

 4

2.44 (1.26–4.74)

1.32 (0.84–2.08)

1.62 (1.12–2.34)

 

 5

2.35 (1.01–5.51)

1.36 (0.78–2.38)

1.59 (1.01–2.51)

 
  1. a Analysis based on 25,038 REGARDS participants with non-missing data on exposure and covariates. Models adjusted for age, sex, race (all model only), education, region, income, tobacco use, alcohol use, and baseline chronic medical conditions, and hs-CRP
  2. b N = number of cancer death events
  3. c Interaction significance between race*factor (i.e., metabolic syndrome, high waist circumference (WC), and metabolic syndrome components) using Wald test
  4. Bold indicates statistically significant at 0.05 alpha level