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Table 1 proportion of clinicopathologic and IHC defined subtypes of BC in Eritrean and Sudanese women

From: Immunohistochemistry defined subtypes of breast cancer in 678 Sudanese and Eritrean women; hospitals based case series

Clinical and tumour characteristics

Origin

Combined both study groups

Eritrean

Sudanese

n

%

n

%

n

%

Histologic type

IDCNST

89

76.7%

492

87.9%

581

85.9%

ILC

11

9.5%

18

3.2%

29

4.3%

others

16

13.8%

50

8.9%

66

9.8%

Pathologic tumour size

pT1

23

19.8%

82

15.5%

105

16.3%

pT2

48

41.4%

248

47.0%

296

46.0%

pT3

37

31.9%

118

22.3%

155

24.1%

pT4

8

6.9%

80

15.2%

88

13.7%

LN involvement

pN0

72

62.1%

198

47.3%

270

50.5%

pN1(1–3)

15

12.9%

86

20.5%

101

18.9%

pN2(3–9)

16

13.8%

78

18.6%

94

17.6%

pN3(>9)

13

11.2%

57

13.6%

70

13.1%

Grading

GI

10

8.6%

20

3.6%

30

4.4%

GII

46

39.7%

306

54.6%

352

52.1%

GIII

60

51.7%

234

41.8%

294

43.5%

LVI

NO

44

37.9%

264

46.9%

308

45.2%

unknown

6

5.1%

111

19.8%

117

17.3%

YES

56

48.3%

185

15.2%

102

35.5%

ER

ER negative.

59

50.9%

308

55.0%

367

54.3%

ER positive.

57

49.1%

252

45.0%

309

45.7%

PR

PR negative

69

59.5%

346

61.8%

415

61.4%

PR positive

47

40.5%

214

38.2%

261

38.6%

HR

HR positive

57

49.1%

257

45.9%

314

46.4%

HR negative

59

50.9%

303

54.1%

362

53.6%

HER2

negative

82

70.7%

296

71.3%

378

71.2%

positive

34

29.3%

119

28.7%

153

28.8%

 

Missing

0

0

147

–

147

–

IHC based breast cancer subtype

Luminal A-like

43

37.1%

153

36.9%

196

36.9%

Luminal B-like

14

12.1%

54

13.0%

68

12.8%

HER2 enriched

20

17.2%

65

15.7%

85

16.0%

TNBC

39

33.6%

143

34.5%

182

34.3%

  1. IDCNST invasive ductal carcinoma, no special type, ILC invasive lobular carcinoma, TNBC Triple negative Breast cancer