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Fig. 2 | BMC Cancer

Fig. 2

From: Concordance of FDG PET/CT metabolic tumour volume versus DW-MRI functional tumour volume with T2-weighted anatomical tumour volume in cervical cancer

Fig. 2

A semi-automated method was used to extract diffusion restricted areas from corresponding b0 and ADC map. VOIs were manually inserted to include the entire tumour. Voxels were automatically separated into 3 groups based on ADC values using a K-means clustering method: solid tumour mass with high cellularity having intermediate ADC, fat and fibrotic tissues having low ADC and normal tissue with low cellularity or cystic tissues having high ADC. FTV(semi-automated) was hence calculated by discarding the fat and fibrotic cluster and the normal tissue cluster, leaving the solid tumour mass cluster. ADC: apparent diffusion coefficient; FTV: functional tumour volume

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