From: Ethnic disparities in breast cancer survival in New Zealand: which factors contribute?
Characteristics | Māori (N = 1283) | Pacific (N = 898) | Non-Māori Non-Pacific (N = 11,489) | p-value | |||||
---|---|---|---|---|---|---|---|---|---|
Crude | Adjusted | Crude | Adjusted | Crude | Adjusted | Crude | Adjusted | ||
Age | Mean (SD) | 54.8 (11.9) | 54.1 (12.7) | 59.6 (14.0) | <0.0001 | ||||
Median (IQR) | 54.0 (16.0) | 53.0 (18.0) | 58.0 (20.0) | ||||||
NZDep 2006 | |||||||||
1–2 | % | 5.0 | 4.7 | 4.5 | 4.1 | 23.4 | 24.2 | <0.0001 | <0.0001 |
3–4 | % | 8.3 | 8.7 | 5.1 | 6.4 | 18.4 | 20.4 | ||
5–6 | % | 15.0 | 16.2 | 10.1 | 12.8 | 21.0 | 23.0 | ||
7–8 | % | 23.7 | 25.3 | 20.5 | 23.3 | 17.8 | 19.0 | ||
9–10 | % | 44.4 | 45.1 | 52.3 | 53.5 | 13.2 | 13.5 | ||
Missing/unknown | % | 3.7 | 7.5 | 6.2 | |||||
Area of residence | |||||||||
Urban | % | 73.0 | 78.3 | 85.4 | 94.9 | 78.3 | 86.4 | <0.0001 | <0.0001 |
Rural | % | 20.1 | 21.7 | 2.7 | 5.1 | 12.0 | 13.6 | ||
Missing/unknown | % | 6.9 | 11.9 | 9.7 | |||||
Register | |||||||||
Auckland | % | 63.6 | 62.7 | 93.5 | 92.5 | 77.7 | 77.9 | <0.0001 | <0.0001 a |
Waikato | % | 36.4 | 37.4 | 6.5 | 7.5 | 22.3 | 22.1 | ||
Screen-detected | % | 36.1 | 35.0 | 31.0 | 29.9 | 39.3 | 39.5 | <0.0001 | <0.0001 a |
<45 years old | % | 2.4 | 2.8 | 0.5 | 0.9 | 8.2 | 8.1 | <0.0001 | <0.0001 a |
45-69 years old | % | 49.7 | 49.2 | 47.0 | 47.2 | 54.9 | 55.0 | <0.0001 | <0.0001 a |
70+ years old | % | 9.5 | 5.2 | 7.3 | 3.6 | 15.5 | 15.9 | 0.01 | <0.0001 a |
Stage at diagnosis | |||||||||
I | % | 34.8 | 34.9 | 25.6 | 25.7 | 43.6 | 43.6 | <0.0001 | <0.0001 a |
II | % | 39.8 | 40.3 | 40.5 | 41.0 | 38.4 | 38.4 | ||
III | % | 17.9 | 17.3 | 23.2 | 22.4 | 13.9 | 14.1 | ||
IV | % | 7.3 | 7.55 | 10.6 | 10.9 | 3.9 | 3.9 | ||
Missing/unknown | % | 0.1 | 0.1 | 0.2 | |||||
Grade | |||||||||
I | % | 20.6 | 21.8 | 15.7 | 17.2 | 24.1 | 24.7 | <0.0001 | <0.0001 a |
II | % | 46.7 | 51.1 | 42.8 | 47.9 | 44.0 | 46.9 | ||
III | % | 26.9 | 27.1 | 35.0 | 34.9 | 26.8 | 28.4 | ||
Missing/unknown | % | 5.8 | 6.6 | 5.1 | |||||
Histology | |||||||||
Ductal | % | 83.6 | 82.8 | 83.9 | 83.0 | 78.8 | 79.5 | <0.0001 | 0.2 a |
Lobular | % | 7.8 | 8.9 | 6.5 | 7.9 | 12.1 | 12.5 | ||
Other | % | 7.9 | 8.3 | 8.6 | 9.1 | 8.0 | 8.0 | ||
Missing/unknown | % | 0.8 | 1.1 | 1.1 | |||||
Hormone receptor status | |||||||||
ER+/PR+ | % | 67.7 | 67.8 | 65.6 | 65.8 | 63.2 | 63.9 | <0.0001 | 0.03 a |
ER+/PR- | % | 11.9 | 14.0 | 8.1 | 11.5 | 14.8 | 15.9 | ||
ER−/PR+ | % | 1.4 | 2.3 | 1.3 | 2.5 | 1.4 | 2.2 | ||
ER−/PR- | % | 16.3 | 15.9 | 20.7 | 20.2 | 17.8 | 18.1 | ||
Missing/unknown | % | 2.7 | 4.2 | 2.8 | |||||
HER-2 | |||||||||
Positive | % | 16.1 | 16.2 | 20.8 | 21.3 | 11.8 | 13.6 | <0.0001 | <0.0001 a |
Equivocal | % | 1.8 | 13.6 | 1.0 | 15.3 | 1.7 | 13.2 | ||
Negative | % | 65.6 | 70.3 | 56.4 | 63.4 | 64.0 | 73.3 | ||
Missing/unknown | % | 16.5 | 21.8 | 22.5 | |||||
C3 index scores | |||||||||
0 | % | 69.8 | 65.6 | 72.4 | 67.5 | 79.5 | 80.3 | <0.0001 | <0.0001 a |
1 | % | 9.6 | 10.3 | 8.4 | 9.2 | 7.9 | 7.7 | ||
2 | % | 8.6 | 24.1 | 7.8 | 23.3 | 5.3 | 11.9 | ||
Treatment facility type | |||||||||
Public | % | 83.8 | 86.6 | 84.2 | 87.3 | 53.2 | 52.6 | <0.0001 | <0.0001 a |
Private | % | 16.2 | 13.4 | 15.8 | 12.7 | 46.8 | 47.4 | ||
Time to first treatment (days)b | Mean (SD) | 41.2 (54.9) | 41.5 | 62.5 (154.6) | 62.1 | 30.4 (54.9) | 30.3 | <0.0001 | <0.0001 c |
Median (IQR) | 33.0 (25.0) | 34.0 (30.0) | 23.0 (23.0) | ||||||
Loco-regional therapy | |||||||||
Breast conserving surgery + radiotherapy | % | 37.4 | 38.2 | 27.2 | 32.1 | 42.7 | 42.2 | <0.0001 | <0.0001 c |
Breast conserving surgery alone | % | 7.4 | 8.1 | 6.4 | 8.0 | 9.1 | 8.9 | ||
Mastectomy + radiotherapy | % | 20.8 | 17.6 | 23.5 | 16.4 | 16.4 | 17.3 | ||
Mastectomy alone | % | 25.9 | 27.7 | 28.6 | 31.1 | 25.7 | 25.3 | ||
No primary surgery | % | 8.5 | 8.4 | 14.4 | 12.4 | 6.1 | 6.3 | ||
Systemic therapy | |||||||||
Chemotherapy + hormonal/biological treatment | % | 27.5 | 20.9 | 26.8 | 16.8 | 22.3 | 23.8 | <0.0001 | <0.0001 c |
Chemotherapy alone | % | 10.9 | 10.7 | 9.0 | 6.3 | 9.6 | 9.9 | ||
Hormonal/biological treatment alone | % | 39.7 | 42.6 | 38.9 | 44.8 | 40.6 | 39.8 | ||
None | % | 21.9 | 25.92 | 25.3 | 32.1 | 27.5 | 26.5 |