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Table 2 Incidence rates of breast cancer by birth year in Chinese women

From: Incidence of breast cancer in Chinese women exposed to the 1959–1961 great Chinese famine

 

All subjects

(N = 59,060)

Birth year

1955–1958 (N = 25,836)

1959–1962 (N = 17,772)

1963–1966 (N = 15,452)

Cancer in situ

 Person-years

302,019

136,574

88,645

76,800

 No. of cases

43

18

17

8

 Incidence (95%CI)

14.2 (10.6, 19.2)

13.2 (8.3, 20.9)

19.2 (11.9, 30.8)

10.4 (5.2, 20.8)

 Adjusted HR (95%CI)

 

1.00

1.06 (0.73, 1.51)

0.95 (0.53, 1.71)

Invasive cancer

 Person-years

302,129

136,620

88,691

76,817

 No. of cases

330

150

102

78

 Incidence (95%CI)

109.2 (98.0, 121.7)

109.8 (93.6, 128.8)

115.0 (94.7, 139.6)

101.5 (81.3, 126.8)

 Adjusted HR (95%CI)

 

1.00

1.85 (0.69, 1.98)

1.36 (0.25, 7.34)

All breast cancer

 Person-years

302,019

136,574

88,645

76,800

 No. of cases

373

168

119

86

 Incidence (95%CI)

123.5 (111.6, 136.7)

123.0 (105.7, 143.1)

134.2 (112.2, 160.7)

111.9 (90.6, 138.3)

 Adjusted HR (95%CI)

 

1.00

1.13 (0.80, 1.58)

0.98 (0.57, 1.73)

  1. a Adjusted for age (as a continuous variable), educational level (Primary school or below / Middle School / Technical school / High school / College or above, dummy variables), in marriage (yes /no), regular menstrual cycle (yes / no), breastfeeding (ever / never) and family history of breast cancer (yes / no)