Fig. 6

The biological function of the stable clones when iASPP or Sertad1 was knocked down in multiple cell lines. a. iASPP was knocked down in the K562,U937 and KG1a leukemic cells. b. Sertad1 was knocked down in the K562,U937 and KG1a leukemic cells. c. The proliferation of cells after iASPP was knocked down followed by incubated for 72 h in multiple leukemic cells. d. The proliferation of cells after Setad1 was knocked down followed by incubated for 72 h in multiple leukemic cells. e. The percentage of G0/G1 stage after iASPP was knocked down followed by incubated for 48 h in multiple leukemic cells. f. The percentage of G0/G1 stage after Sertad1 was knocked down followed by incubated for 48 h in multiple leukemic cells. g. The percentage of apoptosis after iASPP was knocked down followed by incubated for 48 h with etoposide in multiple leukemic cells.(etoptoside in K562 was 2 μg/ml, U937 was 0.4 μg/ml, KG1a was 4 μg/ml). h. The percentage of apoptosis after Sertad1 was knocked down followed by incubated for 48 h with etoposide in multiple leukemic cells. (etoptoside in K562 was 2 μg/ml, U937 was 0.4 μg/ml, KG1a was 4 μg/ml).All data are representive of 3 independent experiments. (* represent P < 0.05)