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Table 2 Univariate and multivariate analysis of patient- and treatment-related risk factors for neck muscle spasm

From: Patient- and treatment-related risk factors associated with neck muscle spasm in nasopharyngeal carcinoma patients after intensity-modulated radiotherapy

 

P value

OR (95% CI)

Univariate analysis

 Sex

  

  Male

 

Ref

  Female

0.003

2.620 (1.387, 4.949)

 Age (years)

   ≤ 41

 

Ref

   > 41

0.472

1.250 (0.681, 2.297)

 T stage

  T1–2

 

Ref

  T3–4

0.358

1.440 (0.662, 3.131)

 N stage

  N0–1

 

Ref

  N2–3

0.002

2.846 (1.445, 5.607)

 Smoking status

  Yes

0.799

0.919 (0.481, 1.758)

  No

 

Ref

 Drinking status

  Yes

0.851

1.083 (0.472, 2.485)

  No

 

Ref

 Induction chemotherapy

  Yes

0.839

1.065 (0.581, 1.953)

  No

 

Ref

 Concurrent chemotherapy

  Yes

0.851

0.924 (0.402, 2.120)

  No

 

Ref

 Neck dissection

  Yes

0.332

1.963 (0.502, 7.671)

  No

 

Ref

 D mean

< 0.001

1.002 (1.001, 1.003)

 D min

< 0.001

1.001 (1.001, 1.001)

 D max

0.007

1.001 (1.000, 1.002)

 V20a

< 0.001

1.085 (1.045, 1.127)

 V25

< 0.001

1.085 (1.046, 1.125)

 V30

< 0.001

1.083 (1.046, 1.121)

 V35

< 0.001

1.081 (1.045, 1.118)

 V40

< 0.001

1.082 (1.046, 1.120)

 V45

< 0.001

1.085 (1.048, 1.122)

 V50

< 0.001

1.118 (1.068, 1.171)

 V55

< 0.001

1.148 (1.096, 1.202)

 V60

< 0.001

1.192 (1.133, 1.255)

 V65

< 0.001

1.106 (1.076, 1.136)

 V70

< 0.001

1.126 (1.072, 1.183)

 V75

0.653

1.173 (0.585, 2.349)

 V80

0.999

0.000 (0.000, 0.000)

 D20b

< 0.001

1.004 (1.003, 1.005)

 D25

< 0.001

1.005 (1.003, 1.006)

 D30

< 0.001

1.005 (1.003, 1.006)

 D35

< 0.001

1.005 (1.004, 1.007)

 D40

< 0.001

1.005 (1.004, 1.007)

 D45

< 0.001

1.005 (1.004, 1.007)

 D50

< 0.001

1.005 (1.003, 1.007)

 D55

< 0.001

1.003 (1.002, 1.005)

 D60

0.001

1.002 (1.001, 1.003)

 D65

0.001

1.001 (1.000, 1.002)

 D70

< 0.001

1.001 (1.000, 1.001)

 D75

< 0.001

1.001 (1.000, 1.001)

 D80

< 0.001

1.001 (1.000, 1.001)

Multivariate analysis

 Sex

  Male

 

Ref

  Female

0.024

3.044 (1.157, 8.012)

 N stage

  N0–1

 

Ref

  N2–3

0.035

2.823 (1.078, 7.398)

 V60

< 0.001

1.185 (1.126, 1.246)

  1. Abbreviations: Dmean mean dose to the sternocleidomastoid muscle, Dmax maximum dose to the sternocleidomastoid muscle, V20 a percentage of the sternocleidomastoid muscle volume that received >20 Gy, D20 b dose to 20% of the sternocleidomastoid muscle volume; other dosimetric parameters are reported in a similar manner
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BMC Cancer

ISSN: 1471-2407

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