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Fig. 4 | BMC Cancer

Fig. 4

From: Multi-region and single-cell sequencing reveal variable genomic heterogeneity in rectal cancer

Fig. 4

Individual differences between two patients. a The consensus copy number profiles of two patients. Each patient had a specific individual large-scale copy number pattern. b The hierarchical clustering using Euclidean distance and ward.D method showed that single tumor cells were grouped into two populations according to two patients. c The PCA showed that single tumor cells were divided into two clusters according to two patients. d The Venn diagram of mutations from two patients. Two patients merely had TTN and SYNE1 mutated genes in common. e GO-BP analyses of mutated genes in two patients. The top five biological processes of the two patients were quite different and x axis was labeled by the number of mutated genes involved in each process, p < 0.05

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