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Table 1 Fold change (FC) and p-values of the 18 significant miRNA

From: Robust expression of tumor suppressor miRNA’s let-7 and miR-195 detected in plasma of Saudi female breast cancer patients

 

Triple Negative

Luminal

miRNA ID

2^-(TNBC-C)A

p (Corr) TNBC vs CP

Regulation (TNBC vs C)

FC (TNBC vs C)F

2^-(L-C)B

p (Corr) L vs C P

Regulation (L vs C)

FC (L vs C)F

hsa-let-7b-5p

2.14

0.006

Up

2.14

2.29

0.000

Up

2.29

hsa-let-7c-5p

1.72

0.031

Up

1.72

1.95

0.001

Up

1.95

hsa-let-7i-5p

1.71

0.008

Up

1.71

1.60

0.008

Up

1.60

hsa-miR-15a-5p

2.01

0.006

Up

2.01

0.91

0.977

Up

−1.09

hsa-miR-16-5p

2.20

0.000

Up

2.20

1.68

0.008

Up

1.68

hsa-miR-195-5p

1.84

0.004

Up

1.84

1.60

0.011

Up

1.60

hsa-miR-199a-3p

0.36

0.002

Down

−2.81

0.36

0.003

Down

−2.80

hsa-miR-199a-5p

0.46

0.021

Down

−2.19

0.25

0.001

Down

−3.94

hsa-miR-19a-3p

1.81

0.006

Up

1.81

1.29

0.205

Up

1.29

hsa-miR-19b-3p

1.86

0.006

Up

1.86

1.27

0.203

Up

1.27

hsa-miR-210-3p

1.91

0.000

Up

1.91

1.23

0.646

Up

1.23

hsa-miR-22-3p

1.93

0.006

Up

1.93

1.08

0.083

Up

1.08

hsa-miR-25-3p

2.02

0.001

Up

2.02

2.01

0.001

Up

2.01

hsa-miR-29c-3p

1.66

1.010

Up

1.66

1.19

0.203

Up

1.19

hsa-miR-328-3p

1.58

0.563

Up

1.58

20.96

0.000

Up

20.96

hsa-miR-340-5p

0.65

0.043

Down

−1.54

0.55

0.008

Down

−1.81

hsa-miR-489-3p

1.85

0.057

Up

1.85

2.26

0.000

Up

2.26

hsa-miR-7-5p

2.30

0.003

Up

2.30

2.01

0.012

Up

2.01

  1. TNBC Triple Negative Breast Cancer
  2. C - Disease-free individuals used as Controls
  3. L - Luminal Breast Cancer
  4. A: 2^-(TNBC-N) represents 2^ddCt values of Triple Negative patient’s samples as compared to those of disease-free individuals
  5. P: Corrected p-values ≤ 0.01 for a given pair of conditions are shown in bold
  6. F: Fold change values ≥ 1.5 are shown in bold
  7. B: 2^-(L-N) represents 2^ddCt values of Luminal patients’ samples as compared to those disease-free individuals
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BMC Cancer

ISSN: 1471-2407

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