Fig. 5

Differences in lymphatic microvessel density between tumors with and without lymphatic invasion. The lymphatic microvessel density in tumors with lymphatic invasion was significantly higher compared with that in tumors without lymphatic invasion. LMVD was a significant risk factor for lymphatic invasion in hindgut neuroendocrine tumors (Mann–Whitney U test, P < 0.001; values are expressed as the mean ± standard deviation)